New findings from Mass General Brigham investigators said that taking a daily multivitamin over a long period may help lower the risk of developing hypertension and may also reduce blood pressure (BP) in some older adults.
From the secondary analysis of data from the Cocoa Supplement and Multivitamin Outcomes Study (COSMOS), researchers showed moderate but significant benefits for people with lower-quality diets and for those with normal blood pressure at the
beginning of the study. The American Journal of Hypertension published the study’s findings.Even so, the analysis
determined that, for the overall study population, daily multivitamin use did
not impact hypertension risk or blood pressure in every older adult.
COSMOS is a randomised and
placebo-controlled clinical trial designed to explore how cocoa extract and
multivitamin supplements influence health in older adults in the U.S.
For this analysis, the
investigators focused on 8,905 participants who did not have hypertension at
the start of the study and who were assigned to take either Centrum Silver or a
placebo each day for a median period of 3.4 years.
The team also assessed changes in
blood pressure over a two-year span in two additional groups that included 529
participants with clinic-based measurements and 994 participants who recorded
their measurements at home.
Overall, the investigators
found no differences in self-reported incident hypertension between the
multivitamin and placebo groups. Multivitamins lowered the risk of hypertension
in participants with comparatively lower diet quality, as measured by the Alternative
Healthy Eating Index (AHEI) and the Alternate Mediterranean Diet (aMED) scores.
In addition, participants
with normal BP at baseline taking a daily multivitamin experienced small,
significant reductions in BP measurements over two years.
The authors propose that
further research is required to examine the effects of a daily multivitamin in
younger and middle-aged adults and across different populations based on
nutritional status.
Corresponding author Rikuta
Hamaya, MD, PhD, MS, of the Division of Preventive Medicine in the Mass General
Brigham Department of Medicine, in a reaction, said, “Our findings suggest that
a daily multivitamin may not be a one-size-fits-all solution for controlling
blood pressure but could be beneficial for important subsets of older adults.”

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